Linked Life Data

2619723

Source:http://linkedlifedata.com/resource/pubmed/id/2619723

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1990-2-26
pubmed:abstractText
A new peptide, obtained by chemical synthesis, inhibits porcine pancreatic elastase activity "in vitro" with an IC50 of 24 mmol/l. The effect of the peptide was also tested on human plasma elastase by using plasmas with different levels of alpha-1-antitrypsin. The synthetic peptide apparently decreased the amount of normal plasma elastase, assayed by an immunoenzymatic method, with a dose-dependent effect and an IC50 of 13 mmol/l. In plasma with higher amounts of alpha-1-antitrypsin the IC50 value was 18 mmol/l.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
505-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
A new synthetic peptide with elastase inhibiting effect.
pubmed:affiliation
Institute of Biological Chemistry, University of Padova, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't