Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1978-7-15
|
| pubmed:abstractText |
L cells (L-As subline) have been adapted to a temperature of 4 degrees C. In the cold-adapted cells, designated LC3, greater amounts of infectious herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) were synthesized than in the original L-As cells or in another control L-cell line. Two strains of HSV-1 reached higher infectious titres in LC3 cells grown at 36 degrees C than in those grown at 32 degrees C. The HSV-2 strain tested replicated in LC-3 cells grown at 32 degrees C better than at higher temperature. Increased reproduction of HSV in LC3 cells was not due to enhanced adsorption of virions on the cells as compared with control L cells. The multiplication of cold-adapted LC3 cells was and was not more intensive than of L-As and control L cells, respectively. The virological results are confronted with known physiological properties of cold-adapted cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0001-723X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
113-22
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:26196-Adaptation, Physiological,
pubmed-meshheading:26196-Adsorption,
pubmed-meshheading:26196-Cell Division,
pubmed-meshheading:26196-Cold Temperature,
pubmed-meshheading:26196-Cytopathogenic Effect, Viral,
pubmed-meshheading:26196-L Cells (Cell Line),
pubmed-meshheading:26196-Simplexvirus
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
Increased susceptibility to infection with herpes simplex virus types 1 and 2 of cold-adapted L cells.
|
| pubmed:publicationType |
Journal Article
|