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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
|
pubmed:dateCreated |
1990-3-8
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pubmed:abstractText |
Addition of sodium nitrate to growing cultures of Aspergillus parasiticus (ATCC 36537) induces the synthesis of enzymes involved in nitrate assimilation (NO3- reductase), of enzymes in the pentose pathway (glucose-6-phosphate dehydrogenase), and of enzymes in the mannitol cycle (mannitol- and mannitol-1-phosphate dehydrogenases). Addition of NO3- also causes a dose-dependent suppression of synthesis of the polyketide secondary metabolite, versicolorin A. We suggest that in the presence of NO3- plus peptone, the cytoplasmic NADPH/NADP ratio may be elevated, resulting in increased conversion of malonyl coenzyme A to fatty acid rather than to polyketide.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anthraquinones,
http://linkedlifedata.com/resource/pubmed/chemical/Mannitol Dehydrogenases,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrate Reductase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrate Reductases,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrates,
http://linkedlifedata.com/resource/pubmed/chemical/versicolorins
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0301-486X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2615792-Anthraquinones,
pubmed-meshheading:2615792-Aspergillus,
pubmed-meshheading:2615792-Mannitol Dehydrogenases,
pubmed-meshheading:2615792-Nitrate Reductase,
pubmed-meshheading:2615792-Nitrate Reductases,
pubmed-meshheading:2615792-Nitrates,
pubmed-meshheading:2615792-Pentose Phosphate Pathway
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pubmed:year |
1989
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pubmed:articleTitle |
Nitrate induces enzymes of the mannitol cycle and suppresses versicolorin synthesis in Aspergillus parasiticus.
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pubmed:affiliation |
Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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