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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1990-1-25
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pubmed:abstractText |
A cross-sectional study of gallstone disease, ascertained by ultrasonography, comprised 4581 men and women of Danish origin, aged 30, 40, 50, and 60 years, of whom 3608 (79%) attended the investigation. The prevalence was assessed in relation to plasma concentrations of total cholesterol, high-density-lipoprotein cholesterol, low-density-lipoprotein cholesterol, and triglyceride. In the univariate analysis gallstone disease was significantly associated with high triglyceride and low high-density-lipoprotein cholesterol. No significant association among gallstones and total cholesterol and low-density-lipoprotein cholesterol was seen. In multivariate analyses triglyceride lost its significant association with gallstone disease, whereas total cholesterol became negatively associated with gallstones. This was seen for both the high-density-lipoprotein and the low-density-lipoprotein fraction of cholesterol. The difficulties in analysing present plasma lipid status with gallstone prevalence must be stressed. Looking only at small gallstones, which could represent newly formed stones, a change from a negative to a positive association between gallstone and both low-density-lipoprotein cholesterol and total cholesterol was seen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0036-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
916-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2595254-Adult,
pubmed-meshheading:2595254-Aged,
pubmed-meshheading:2595254-Cholelithiasis,
pubmed-meshheading:2595254-Cholesterol, HDL,
pubmed-meshheading:2595254-Cholesterol, LDL,
pubmed-meshheading:2595254-Cross-Sectional Studies,
pubmed-meshheading:2595254-Denmark,
pubmed-meshheading:2595254-Female,
pubmed-meshheading:2595254-Humans,
pubmed-meshheading:2595254-Lipids,
pubmed-meshheading:2595254-Male,
pubmed-meshheading:2595254-Middle Aged,
pubmed-meshheading:2595254-Triglycerides
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pubmed:year |
1989
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pubmed:articleTitle |
Gallstones and plasma lipids in a Danish population.
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pubmed:affiliation |
Dept. of Surgical Gastroenterology, University of Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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