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| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0242767 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0018956 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C1186763 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0229601 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0085862 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C0018284 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C1333104 | lld:lifeskim |
| pubmed-article:2586530 | lifeskim:mentions | umls-concept:C1519697 | lld:lifeskim |
| pubmed-article:2586530 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:2586530 | pubmed:dateCreated | 1990-1-11 | lld:pubmed |
| pubmed-article:2586530 | pubmed:abstractText | At least two separate but interdependent events are required to attain autonomous growth as a consequence of ectopic expression of the multilineage colony-stimulating factor gene in hematopoietic progenitor cells. The rate at which the second event occurs is more than 3 orders of magnitude higher in precursor cell lines (FDC-P1 or FDC-P2) than in stem cell lines (FDC-Pmix). Autonomous, but not density-dependent, growth is tightly coupled to tumorigenicity in precursor cells; however, neither growth-factor-independent nor autonomously growing stem cell lines are tumorigenic. | lld:pubmed |
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| pubmed-article:2586530 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2586530 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2586530 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2586530 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2586530 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2586530 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:OstertagWW | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:KlugeNN | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:DeLamarterJ... | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:SpooncerEE | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:StockingCC | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:LakerCC | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:DexterMM | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:FranzM JMJ | lld:pubmed |
| pubmed-article:2586530 | pubmed:author | pubmed-author:HoweD HDH | lld:pubmed |
| pubmed-article:2586530 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2586530 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:2586530 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2586530 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2586530 | pubmed:pagination | 5746-9 | lld:pubmed |
| pubmed-article:2586530 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2586530 | pubmed:meshHeading | pubmed-meshheading:2586530-... | lld:pubmed |
| pubmed-article:2586530 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2586530 | pubmed:articleTitle | Rates of mutation to growth factor autonomy and tumorigenicity differ in hematopoietic stem and precursor cells expressing the multilineage colony-stimulating factor gene. | lld:pubmed |
| pubmed-article:2586530 | pubmed:affiliation | Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Universität Hamburg, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:2586530 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2586530 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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