Linked Life Data

2579719

Source:http://linkedlifedata.com/resource/pubmed/id/2579719

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1985-4-30
pubmed:abstractText
Cells from three parotid acinic cell carcinomas were compared stereologically with normal parotid acinar cells. The morphometric studies revealed that the granular volume density was increased in the tumor cells. The cells contained more granules, but the mean granule diameter was considerably less, compared with normal controls. On the other hand, no difference in cell volume or nuclear volume density could be found. Although morphologically similar to normal acinar cells, the tumor cells had a much lower content of amylase. However, in a batch-incubated system, amylase secretion could be elicited with noradrenaline from the tumor cells. Furthermore, noradrenaline stimulation increases tumor tissue cyclic AMP content dramatically. The current study demonstrated the similarity between normal acinar cells and acinic cell tumor cells: the latter respond to physiologic secretion stimuli with an increased tissue level of cyclic AMP accompanied by amylase release.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1706-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Ultrastructural morphometry and secretory behavior of acinic cell carcinoma.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't