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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1990-1-26
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pubmed:abstractText |
Dopaminergic interplexiform neurons have been identified in the inner nuclear layer of goldfish retina, with tyrosine hydroxylase (TH) immunocytochemistry in whole-mounted retinae and in cryosections. The neurotoxin 1-methyl-4-phenylpyridinium ion (MPP+), which selectively damages dopaminergic neurons in mammals, caused a marked depletion of TH immunoreactivity in goldfish retina. Three days after intravitreal injection, retinae showed no significant decrease in the number of TH-positive neurons. However most of the TH-immunoreactive cell bodies showed an evident depletion of TH immunoreactivity and their processes, ramified in the inner and outer plexiform layers, disappeared almost completely.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2574839-1-Methyl-4-phenylpyridinium,
pubmed-meshheading:2574839-Animals,
pubmed-meshheading:2574839-Cyprinidae,
pubmed-meshheading:2574839-Dopamine,
pubmed-meshheading:2574839-Goldfish,
pubmed-meshheading:2574839-Immunohistochemistry,
pubmed-meshheading:2574839-Retina,
pubmed-meshheading:2574839-Tyrosine 3-Monooxygenase
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pubmed:year |
1989
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pubmed:articleTitle |
Tyrosine hydroxylase immunohistochemistry in the normal and 1-methyl-4-phenyl-tetrahydropyridine (MPP+)-treated retina of goldfish.
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pubmed:affiliation |
Department of Biology, University of Bologna, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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