Linked Life Data

2573312

Source:http://linkedlifedata.com/resource/pubmed/id/2573312

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-12-4
pubmed:abstractText
Administration of the beta 2 adrenergic agonists fenoterol, salbutamol and terbutaline to volunteers significantly reduced plasma potassium concentration in a double-blind crossover study. There was no consistent effect of the three active compounds on erythrocyte sodium concentration. Storage of whole blood at 4 degrees C increased erythrocyte sodium concentration by 33% after 2 h; this could explain the differences between this and another study of the effects of beta 2 adrenergic agonists on erythrocyte sodium concentration. We conclude that the human erythrocyte is unsuitable as an indirect in vivo model to demonstrate stimulation of cellular sodium potassium transport mediated by beta 2 adrenergic agonists.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
26 ( Pt 5)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
444-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Unsuitability of the human erythrocyte as a model for in vivo sodium transport activation by beta 2 adrenergic agonists.
pubmed:affiliation
Department of Medicine, Wellington School of Medicine, New Zealand.
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial, Research Support, Non-U.S. Gov't