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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1989-8-1
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pubmed:abstractText |
In rabbit jejunal arteries, the membrane potential of single smooth muscle cells decreased on the application of noradrenaline 3 mumol/l. LY 171555 1 mumol/l did not change, whereas SKF 38393 10 mumol/l reversed the effect of noradrenaline. When prostaglandin F2 alpha (PGF2 alpha) was used to evoke depolarization in the presence of prazosin 0.1 mumol/l, rauwolscine 1 mumol/l and propranolol 1 mumol/l, both SKF 38393 10 mumol/l and dopamine 10 mumol/l repolarized the membrane. SCH 23390 1 mumol/l antagonized the effects of SKF 38393 10 mumol/l and dopamine 10 mumol/l. Thus, the change in membrane potential is mediated by a DA1-receptor.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-p...,
http://linkedlifedata.com/resource/pubmed/chemical/Benzazepines,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprost,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Ergolines,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Quinpirole,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0028-1298
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
339
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
483-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2567968-2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine,
pubmed-meshheading:2567968-Animals,
pubmed-meshheading:2567968-Arteries,
pubmed-meshheading:2567968-Benzazepines,
pubmed-meshheading:2567968-Dinoprost,
pubmed-meshheading:2567968-Dopamine,
pubmed-meshheading:2567968-Dopamine Agents,
pubmed-meshheading:2567968-Dopamine Antagonists,
pubmed-meshheading:2567968-Ergolines,
pubmed-meshheading:2567968-Female,
pubmed-meshheading:2567968-Jejunum,
pubmed-meshheading:2567968-Male,
pubmed-meshheading:2567968-Membrane Potentials,
pubmed-meshheading:2567968-Muscle, Smooth, Vascular,
pubmed-meshheading:2567968-Norepinephrine,
pubmed-meshheading:2567968-Quinpirole,
pubmed-meshheading:2567968-Rabbits,
pubmed-meshheading:2567968-Receptors, Dopamine
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pubmed:year |
1989
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pubmed:articleTitle |
Dopamine inhibits prostaglandin F2 alpha-induced depolarization of rabbit jejunal arteries via activation of DA1-receptors.
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pubmed:affiliation |
Department of Pharmacology, University of Freiburg, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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