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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8654
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pubmed:dateCreated |
1989-8-10
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pubmed:abstractText |
To examine whether cytomegalovirus (CMV) infection could accelerate progression of human immunodeficiency virus (HIV) infection to AIDS, serological studies were done on 108 HIV-infected haemophiliacs. In the 1.3-9 years from time of first recognised HIV seroconversion, the age-adjusted risk of CDC group IV disease in CMV-seropositive patients was 2.5 times that in CMV-seronegative patients. CMV-seropositive patients were also more likely to have detectable p24 antigenaemia. Survival analysis showed that CMV-seropositive patients were at greater risk of HIV disease than CMV-seronegative patients from about 2 years after HIV seroconversion. Thus CMV infection is associated with a more rapid progression to HIV disease.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2567870-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2567870-Adolescent,
pubmed-meshheading:2567870-Adult,
pubmed-meshheading:2567870-Child,
pubmed-meshheading:2567870-Cytomegalovirus Infections,
pubmed-meshheading:2567870-HIV Seropositivity,
pubmed-meshheading:2567870-Hemophilia A,
pubmed-meshheading:2567870-Humans,
pubmed-meshheading:2567870-Virus Activation
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pubmed:year |
1989
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pubmed:articleTitle |
Cytomegalovirus infection and progression towards AIDS in haemophiliacs with human immunodeficiency virus infection.
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pubmed:affiliation |
Department of Virology, Royal Free Hospital, School of Medicine, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|