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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8652
|
pubmed:dateCreated |
1989-7-21
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pubmed:abstractText |
In a prospective study to determine the tolerance for and safety of ivermectin therapy for onchocerciasis in a hyperendemic area in Sierra Leone, 28 (32%) of 87 patients had adverse reactions that required treatment with acetylsalicylic acid and antihistamines, but none of the observed adverse reactions were considered life-threatening. A significant relation was found between the frequency and severity of side-effects and the degree of parasite infestation, as quantified by the skin-snip counts. Free administration of ivermectin to severely infected onchocerciasis patients is not recommended without some form of medical supervision.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1439-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2567440-Adult,
pubmed-meshheading:2567440-Animals,
pubmed-meshheading:2567440-Blindness,
pubmed-meshheading:2567440-Drug Evaluation,
pubmed-meshheading:2567440-Eye Diseases,
pubmed-meshheading:2567440-Female,
pubmed-meshheading:2567440-Follow-Up Studies,
pubmed-meshheading:2567440-Humans,
pubmed-meshheading:2567440-Ivermectin,
pubmed-meshheading:2567440-Male,
pubmed-meshheading:2567440-Microfilaria,
pubmed-meshheading:2567440-Onchocerciasis,
pubmed-meshheading:2567440-Prospective Studies,
pubmed-meshheading:2567440-Severity of Illness Index,
pubmed-meshheading:2567440-Skin
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pubmed:year |
1989
|
pubmed:articleTitle |
Side-effects of ivermectin in treatment of onchocerciasis.
|
pubmed:affiliation |
Department of Ophthalmo-immunology, Netherlands Ophthalmic Research Institute, Amsterdam.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|