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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1990-6-26
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pubmed:abstractText |
FRTL-5 rat thyroid cells have receptors for both insulin and IGF-I which can be distinguished in binding studies. The ability of TSH to regulate each in an antiparallel manner is atypical. If these receptors are shown to have independent as well as coordinate activities, studies of the mechanisms of their receptor cross-talk in these cells will be relevant to understanding IGF-I and insulin receptors in other tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cross-Linking Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Somatomedin,
http://linkedlifedata.com/resource/pubmed/chemical/Somatomedins,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin
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pubmed:status |
MEDLINE
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pubmed:issn |
0065-2598
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
261
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-19
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2561505-Animals,
pubmed-meshheading:2561505-Binding, Competitive,
pubmed-meshheading:2561505-Binding Sites,
pubmed-meshheading:2561505-Cell Division,
pubmed-meshheading:2561505-Cell Line,
pubmed-meshheading:2561505-Cross-Linking Reagents,
pubmed-meshheading:2561505-Drug Interactions,
pubmed-meshheading:2561505-Insulin,
pubmed-meshheading:2561505-Insulin-Like Growth Factor I,
pubmed-meshheading:2561505-Protein Binding,
pubmed-meshheading:2561505-Rats,
pubmed-meshheading:2561505-Receptor, Insulin,
pubmed-meshheading:2561505-Receptors, Cell Surface,
pubmed-meshheading:2561505-Receptors, Somatomedin,
pubmed-meshheading:2561505-Somatomedins,
pubmed-meshheading:2561505-Thyroid Gland,
pubmed-meshheading:2561505-Thyrotropin
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pubmed:year |
1989
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pubmed:articleTitle |
Characterization of receptors for insulin and insulin-like growth factor-1 on FRTL-5 thyroid cells.
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pubmed:affiliation |
Diabetes Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article
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