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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1989-10-5
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pubmed:abstractText |
Tail currents through Na+ channels have been measured in inside-out patches from Xenopus laevis oocytes injected with cDNA-derived mRNA coding for the rat brain type II Na+ channel. It is shown that intracellular Mg2+ blocks outward currents in a voltage- and dose-dependent manner with a half blocking concentration between 3 and 4 mM at 0 mV and a voltage dependence of e-fold per 49 mV.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2432253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2432468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2435540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2440317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2443681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2448878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2457094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-2457698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-3754035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-591911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6257898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6259334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6259335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6270629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6323705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2548634-6325946
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0006-3495
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1267-71
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2548634-Animals,
pubmed-meshheading:2548634-Brain,
pubmed-meshheading:2548634-DNA,
pubmed-meshheading:2548634-Female,
pubmed-meshheading:2548634-Glycoproteins,
pubmed-meshheading:2548634-Kinetics,
pubmed-meshheading:2548634-Magnesium,
pubmed-meshheading:2548634-Membrane Potentials,
pubmed-meshheading:2548634-Oocytes,
pubmed-meshheading:2548634-Rats,
pubmed-meshheading:2548634-Sodium Channels,
pubmed-meshheading:2548634-Xenopus laevis
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pubmed:year |
1989
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pubmed:articleTitle |
Intracellular magnesium blocks sodium outward currents in a voltage- and dose-dependent manner.
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pubmed:affiliation |
Max-Planck-Institut für biophysikalische Chemie, Göttingen, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
In Vitro
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