Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 1
pubmed:dateCreated
1989-8-21
pubmed:abstractText
Using an antibody raised against the mitochondrial enzyme cytochrome c oxidase (EC 1.9.3.1), it was possible to visualize microoncocytomas, oncocytic tubules and even single oncocytes in the renal cortex of rats treated with N-nitrosomorpholine, and to localize the lesions to the collecting duct of the nephron. In human specimens, the antibody also stained oncocytomas and oncocytic tubules in the surrounding macroscopically unaffected cortex. Thus, this antibody may be used for detection as well as for investigation of the development of oncocytic lesions in various species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0192-6233
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
46-9
pubmed:dateRevised
2009-7-1
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Immunocytochemical demonstration of cytochrome c oxidase as a marker for renal oncocytes and oncocytomas.
pubmed:affiliation
Institut für Experimentelle Pathologie, Deutsches Krebsforschungszentrum, Heidelberg, FRG.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't