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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1989-7-12
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pubmed:abstractText |
We describe a syncytia assay that utilizes a noninfectious plasmid (pEVd1443) derived from human immunodeficiency virus type I (HIV-I). This plasmid carries a large deletion of gag-pol sequences but expresses HIV-I envelope proteins and induces syncytia following transfection into HeLa-CD4 cells. This plasmid was used to study the effects of mutations in the gp 120 and gp41 portions of the envelope gene of HIV-I.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, gag,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, tat,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Envelope Protein gp120,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Envelope Protein gp160,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Envelope Protein gp41,
http://linkedlifedata.com/resource/pubmed/chemical/Retroviridae Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Envelope Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/tat Gene Products, Human...
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0042-6822
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
170
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
566-70
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2543131-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:2543131-Blotting, Western,
pubmed-meshheading:2543131-Gene Expression Regulation,
pubmed-meshheading:2543131-Gene Products, gag,
pubmed-meshheading:2543131-Gene Products, tat,
pubmed-meshheading:2543131-HIV Antigens,
pubmed-meshheading:2543131-HIV Envelope Protein gp120,
pubmed-meshheading:2543131-HIV Envelope Protein gp160,
pubmed-meshheading:2543131-HIV Envelope Protein gp41,
pubmed-meshheading:2543131-HIV-1,
pubmed-meshheading:2543131-HeLa Cells,
pubmed-meshheading:2543131-Humans,
pubmed-meshheading:2543131-Mutation,
pubmed-meshheading:2543131-Plasmids,
pubmed-meshheading:2543131-Precipitin Tests,
pubmed-meshheading:2543131-Retroviridae Proteins,
pubmed-meshheading:2543131-Transcription Factors,
pubmed-meshheading:2543131-Transfection,
pubmed-meshheading:2543131-Viral Envelope Proteins,
pubmed-meshheading:2543131-tat Gene Products, Human Immunodeficiency Virus
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pubmed:year |
1989
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pubmed:articleTitle |
A syncytia assay for human immunodeficiency virus type I (HIV-I) envelope protein and its use in studying HIV-I mutations.
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pubmed:affiliation |
Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
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pubmed:publicationType |
Journal Article
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