Linked Life Data

2534347

Source:http://linkedlifedata.com/resource/pubmed/id/2534347

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-5-11
pubmed:abstractText
Eleven mycoplasma strains isolated from several organs of diseased seals during the seal epidemic in the Baltic and North Sea in 1988 and the seal epidemic along the New England coast in 1979-1980, were investigated for their cytotoxic potential by inoculation into tracheal organ cultures of SPF and gnotobiotic rats. The mycoplasma strains belonged to three different species. Administration of 2.0 x 10(2) to 4.5 x 10(7) colony forming units of all of the mycoplasma strains caused an inhibition of the ciliary activity and cytopathological changes within the epithelial cells appearing as bleb-like protuberances by observation with the inverted microscope. There was, however, a distinct difference in the strength of the cytopathological changes caused by the three mycoplasma species. Semi- and ultrathin sections of tracheal rings infected with the seal mycoplasma strain 852, observed by light and electron microscopy, revealed a heavy tissue injury of the tracheal epithelium and dumbbell-shaped mycoplasmas adhering to degenerated epithelial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0934-8840
pubmed:author
pubmed:issnType
Print
pubmed:volume
272
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
216-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Investigation of seal mycoplasmas for their cytotoxic potential on tracheal organ cultures of SPF and gnotobiotic rats.
pubmed:affiliation
Institut für Mikrobiologie und Tierseuchen der Tierärztlichen Hochschule Hannover.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't