Linked Life Data

2528485

Source:http://linkedlifedata.com/resource/pubmed/id/2528485

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-10-23
pubmed:abstractText
The effect of dietary triiodothyronine (T3) supplementation (0, 0.1, 0.1, and 1.0 ppm of T3) on the mixed lymphocyte response (MLR) was examined in MHC-matched young Cornell K and sex-linked dwarf (SLD) strain cockerels at ages 6, 9, and 12 weeks. At all ages, MLR in SLD strain cockerels was significantly lower than in the K strain. Supplementation of 6-week-old cockerels with 0.01 and 0.1 ppm of T3 tended to decrease MLR in both strains, whereas the highest dose of T3 had the opposite effect in the K strain and no effect in the SLD strain compared to the control. No significant effects of T3 on MLR were observed in 9-week-old cockerels. A significant main treatment effect of T3 on MLR was observed in 12-week-old cockerels. At this age dietary T3 decreased MLR in both strains. These results show that allo-aggression, a functional parameter of cell-mediated immunity, can be affected by non-MHC controlled strain differences and by the iodothyronine state of these strains.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0145-305X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Effect of dietary triiodothyronine on mixed-lymphocyte responsiveness in young male chickens.
pubmed:affiliation
Department of Poultry and Avian Sciences, Cornell University, Ithaca, NY 4853-5601.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't