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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1989-9-12
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pubmed:abstractText |
The carboxy-terminal five amino acids of the adenovirus type 5 E1A gene product are necessary and sufficient for this protein to become localized in the nuclei of somatic cells. In this report, we demonstrate that E1A contains a second nuclear localization signal, which resides within residues 140 to 185 and which functions in Xenopus oocytes but not Xenopus or mammalian somatic cells. These data demonstrate the cell-type-specific utilization of a nuclear localization signal.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-2835499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-2972538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-3000623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-3023922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-3028247,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-3614197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-46868,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-564468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-6091106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-6096007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-6207484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-7328650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2527314-944701
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4047-50
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1989
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pubmed:articleTitle |
A karyophilic signal sequence in adenovirus type 5 E1A is functional in Xenopus oocytes but not in somatic cells.
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pubmed:affiliation |
Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts 01545.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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