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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
27
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|
pubmed:dateCreated |
1989-8-10
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|
pubmed:abstractText |
Routine examination of a 60-year-old woman with long-lasting rheumatic complaints revealed a granulocytopenia in the differential blood count (1% stab cells, 3% segmented) with a normal total leucocyte count (4,200/microliters). It was caused by a lymphoproliferative disease of the granular lymphocytes, which may also be termed T gamma lymphocytosis because of the predominant phenotype. As the lymphocytosis in blood and bone marrow was of minor degree, the diagnosis was confirmed only by immunocytochemical and molecular-genetic demonstration of clonal expansion of the T gamma lymphocytes. The granulocytopenia gradually became more marked and recurrent infections were noted. Treatment with cyclosporin and cortisone brought about remission of the granulocytopenia.
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pubmed:language |
ger
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0012-0472
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
114
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1064-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2525466-Agranulocytosis,
pubmed-meshheading:2525466-Antigens, Differentiation,
pubmed-meshheading:2525466-Chronic Disease,
pubmed-meshheading:2525466-Clinical Enzyme Tests,
pubmed-meshheading:2525466-Cortisone,
pubmed-meshheading:2525466-Cyclosporins,
pubmed-meshheading:2525466-Diagnosis, Differential,
pubmed-meshheading:2525466-Female,
pubmed-meshheading:2525466-Humans,
pubmed-meshheading:2525466-Immunoglobulin G,
pubmed-meshheading:2525466-Immunohistochemistry,
pubmed-meshheading:2525466-Leukocyte Count,
pubmed-meshheading:2525466-Lymphocytosis,
pubmed-meshheading:2525466-Lymphoproliferative Disorders,
pubmed-meshheading:2525466-Middle Aged,
pubmed-meshheading:2525466-Phenotype,
pubmed-meshheading:2525466-Receptors, Fc,
pubmed-meshheading:2525466-Receptors, IgG,
pubmed-meshheading:2525466-T-Lymphocytes
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|
pubmed:year |
1989
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|
pubmed:articleTitle |
[Chronic granulocytopenia as a main symptom of T gamma-lymphocytosis].
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|
pubmed:affiliation |
Abteilung Hämatologie/Onkologie, Universität Göttingen.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|
