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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1989-5-26
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pubmed:abstractText |
Early postnatal glucocorticoid injections led to a large increase in the number of 5-hydroxytryptamine(5-HT)-immunoreactive small cells in the rat superior cervical ganglion. Tryptophan hydroxylase (TPH) activity in ganglia from animals treated with glucocorticoids was not significantly different from saline-injected controls. Both 5-HT immunoreactivity and TPH activity were decreased in ganglia from animals treated with glucocorticoid and the TPH inhibitor parachlorophenylalanine, but not in animals treated with 5-HT uptake inhibitor fluoxetine. These results suggest that 5-HT is synthesized in the small intensely fluorescent (SIF) cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Fenclonine,
http://linkedlifedata.com/resource/pubmed/chemical/Fluoxetine,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocortisone,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Tryptophan Hydroxylase
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0168-0102
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
276-81
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2523524-Animals,
pubmed-meshheading:2523524-Fenclonine,
pubmed-meshheading:2523524-Fluoxetine,
pubmed-meshheading:2523524-Ganglia, Sympathetic,
pubmed-meshheading:2523524-Hydrocortisone,
pubmed-meshheading:2523524-Immunohistochemistry,
pubmed-meshheading:2523524-Rats,
pubmed-meshheading:2523524-Serotonin,
pubmed-meshheading:2523524-Tryptophan Hydroxylase
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pubmed:year |
1989
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pubmed:articleTitle |
Tryptophan hydroxylase activity and 5-hydroxytryptamine-immunoreactive cells in the superior cervical ganglion of hydrocortisone-treated neonatal rats.
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pubmed:affiliation |
Laboratory of Molecular Neurobiology, Cornell University Medical College, Burke Rehabilitation Center, White Plains, N.Y. 10605.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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