Linked Life Data

2492069

Source:http://linkedlifedata.com/resource/pubmed/id/2492069

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-2-16
pubmed:abstractText
Four tests commonly used in screening strategies to detect colorectal cancer were examined from a cost-effectiveness perspective. Thirteen combinations of the tests were evaluated. Evaluating a positive fecal occult blood test with a double-contrast barium enema study, followed, if necessary, by colonoscopy, is the most cost-effective strategy for individuals at average risk. An alternative screening strategy for higher-risk individuals or for populations in which the frequency of adenomatous polyps is higher is to follow a positive fecal occult blood test directly with colonoscopy. Sensitivity analysis demonstrated that the superior cost-effectiveness of these two strategies compared with the other 11 modeled strategies is almost independent for reasonable alterations in test cost and for the sensitivities and specificities of the procedures. The major contributing factor to the diagnostic cost is the frequency of adenomatous polyps. The major contributing factor to the marginal cost per year of extended life is the frequency of cancer.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0272-989X
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Strategies for screening for colorectal carcinoma.
pubmed:affiliation
Department of Industrial Engineering, University of Wisconsin-Madison.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.