Linked Life Data

2478286

Source:http://linkedlifedata.com/resource/pubmed/id/2478286

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
37
pubmed:dateCreated
1989-12-1
pubmed:abstractText
Phytohemagglutinin-stimulated lymphocytes from 20 young (16-28 years) and 20 old (70-88 years) healthy subjects have been investigated for chromosome aberrations before and after exposure to bleomycin in G2 phase of the cell cycle. No differences were found in unexposed cultures between young and old donors. After treatment with bleomycin the frequency of chromosome aberrations was significantly higher in the old subjects than in the young ones (p less than 0.05). The results suggest that the different interaction between the mutagen and DNA may be caused by the decreased capacity of the excision repair system in the cells of the old individuals.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-7335
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1166-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Chromosome aberrations induced by bleomycin in the lymphocytes of young and old persons].
pubmed:publicationType
Journal Article, English Abstract