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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6241
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pubmed:dateCreated |
1989-11-7
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pubmed:abstractText |
RAP30/74 is a heteromeric general transcription initiation factor which binds to RNA polymerase II. Here we report that preparations of RAP30/74 contain an ATP-dependent DNA helicase whose probable function is to melt the DNA at transcriptional start sites. The sequence of the RAP30 subunit of RAP30/74 indicates that RAP30 may be distantly related to bacterial sigma factors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
341
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
410-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2477704-Amino Acid Sequence,
pubmed-meshheading:2477704-Bacillus subtilis,
pubmed-meshheading:2477704-Base Sequence,
pubmed-meshheading:2477704-Carrier Proteins,
pubmed-meshheading:2477704-Cloning, Molecular,
pubmed-meshheading:2477704-DNA Helicases,
pubmed-meshheading:2477704-Escherichia coli,
pubmed-meshheading:2477704-Genes,
pubmed-meshheading:2477704-Humans,
pubmed-meshheading:2477704-Kinetics,
pubmed-meshheading:2477704-Macromolecular Substances,
pubmed-meshheading:2477704-Molecular Sequence Data,
pubmed-meshheading:2477704-Phosphoproteins,
pubmed-meshheading:2477704-Protein Binding,
pubmed-meshheading:2477704-RNA Polymerase II,
pubmed-meshheading:2477704-Sarcosine,
pubmed-meshheading:2477704-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2477704-Transcription, Genetic
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pubmed:year |
1989
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pubmed:articleTitle |
Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II.
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pubmed:affiliation |
Department of Medical Genetics, University of Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article
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