| pubmed-article:2477376 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0072108 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0026004 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0079183 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0475264 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0175723 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C1081000 | lld:lifeskim |
| pubmed-article:2477376 | lifeskim:mentions | umls-concept:C0008781 | lld:lifeskim |
| pubmed-article:2477376 | pubmed:issue | 4 Pt 1 | lld:pubmed |
| pubmed-article:2477376 | pubmed:dateCreated | 1989-11-2 | lld:pubmed |
| pubmed-article:2477376 | pubmed:abstractText | Human autoimmune sera specific for proliferating cell nuclear antigen (PCNA)/cyclin (auxiliary protein for DNA polymerase delta) demonstrated the presence of epitopes within the macro- and micronuclei of the hypotrichous ciliated protozoa Euplotes eurystomus. Tightly bound PCNA/cyclin was localized at the site of DNA synthesis in macronuclei, the rear zone of the replication band. Starvation or heat shock, conditions that reduce macronuclear replication, resulted in a decrease of PCNA/cyclin in replication bands. Micronuclei also exhibited PCNA/cyclin localization which persisted for a large proportion of the vegetative cell cycle and exhibited significant resistance to adverse culture conditions. Immunoprecipitation of 35S-labeled soluble Euplotes proteins with PCNA/cyclin autoimmune sera revealed a spectrum of low molecular mass proteins. PCNA/cyclin-like proteins have now been observed in the widely divergent species: human, rat, amphibian, yeast, and ciliated protozoa. | lld:pubmed |
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| pubmed-article:2477376 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:2477376 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2477376 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2477376 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:2477376 | pubmed:issn | 0021-9525 | lld:pubmed |
| pubmed-article:2477376 | pubmed:author | pubmed-author:TanE MEM | lld:pubmed |
| pubmed-article:2477376 | pubmed:author | pubmed-author:CacheiroL HLH | lld:pubmed |
| pubmed-article:2477376 | pubmed:author | pubmed-author:OlinsD EDE | lld:pubmed |
| pubmed-article:2477376 | pubmed:author | pubmed-author:OlinsA LAL | lld:pubmed |
| pubmed-article:2477376 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2477376 | pubmed:volume | 109 | lld:pubmed |
| pubmed-article:2477376 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2477376 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2477376 | pubmed:pagination | 1399-410 | lld:pubmed |
| pubmed-article:2477376 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2477376 | pubmed:meshHeading | pubmed-meshheading:2477376-... | lld:pubmed |
| pubmed-article:2477376 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2477376 | pubmed:articleTitle | Proliferating cell nuclear antigen/cyclin in the ciliate Euplotes eurystomus: localization in the replication band and in micronuclei. | lld:pubmed |
| pubmed-article:2477376 | pubmed:affiliation | University of Tennessee-Oak Ridge, Graduate School of Biomedical Sciences 37831. | lld:pubmed |
| pubmed-article:2477376 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2477376 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2477376 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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