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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-2-29
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pubmed:abstractText |
Using intravenously injected horseradish peroxidase (HRP) as tracer, we demonstrate, that--in contrast to other neurohemal regions--the organum vasculosum laminae terminalis (OVLT) is composed of two functionally different divisions. Both parts of the OVLT are endowed with fenestrated capillaries which, however, obviously differ in their permeability for HRP. In one of these portions the neurohemal region remains unlabeled under the experimental conditions used, while the other portion, in analogy to the majority of neurohemal regions, is labeled by the tracer. The functionally different divisions of the OVLT are separated from one another by tanycytic processes and meningeal cells establishing a barrier between the two hemal compartments. The meningeal elements penetrate the organ in the form of an uninterrupted layer; they are continuous with the pia mater and produce large amounts of basal lamina-like material. Furthermore, they provide the delineation of the OVLT against the outer cerebrospinal fluid-containing compartment, a structural feature that is characteristic of both divisions of the OVLT and corresponds to the arrangement of meninges in all other portions of the brain where a blood vessel penetrates its surface.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0302-766X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
250
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
331-47
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2448035-Animals,
pubmed-meshheading:2448035-Axonal Transport,
pubmed-meshheading:2448035-Brain,
pubmed-meshheading:2448035-Cerebrospinal Fluid,
pubmed-meshheading:2448035-Endothelium,
pubmed-meshheading:2448035-Horseradish Peroxidase,
pubmed-meshheading:2448035-Microscopy, Electron,
pubmed-meshheading:2448035-Rats
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pubmed:year |
1987
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pubmed:articleTitle |
Compartments in the organum vasculosum laminae terminalis of the rat and their delineation against the outer cerebrospinal fluid-containing space.
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pubmed:affiliation |
Anatomisches Institut, Universität Kiel, Bundesrepublik Deutschland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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