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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-9-25
|
pubmed:abstractText |
Histamine prolonged the action potential duration and shifted the plateau in an upward direction in guinea-pig ventricular myocytes. Whole cell voltage clamp experiments revealed that histamine increases the amplitude of the inward Ca current with a slight increase in the outward current. Cimetidine but not mepyramine inhibited the effects of histamine. We suggest that histamine increases the Ca current via the mediation of the H2-receptors.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0014-2999
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
138
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
269-72
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading | |
pubmed:year |
1987
|
pubmed:articleTitle |
Histamine increases the Ca current in guinea-pig ventricular myocytes.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|