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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1987-8-5
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pubmed:abstractText |
The diffuse obstructive and infiltrative lung diseases (e.g. bronchitis, asthmatic bronchitis, fibrosing alveolitis, sarcoidosis) contribute significantly to human morbidity and mortality. Disturbance of ventilation and perfusion represents a major physiologic defect in these diseases, resulting in pulmonary hypertension, cor pulmonale and right heart failure. Immunologic and surfactant alterations play a prominent role in these diseases. There is a growing body of evidence indicating that surfactant is a most important material in maintaining airway patency. General concepts regarding these functions in human adult lung diseases and results of investigations of surfactant in an animal model of bleomycin-induced lung fibrosis are presented.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0025-7931
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10-4
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2440082-Animals,
pubmed-meshheading:2440082-Bleomycin,
pubmed-meshheading:2440082-Disease Models, Animal,
pubmed-meshheading:2440082-Lung,
pubmed-meshheading:2440082-Lung Compliance,
pubmed-meshheading:2440082-Lung Diseases,
pubmed-meshheading:2440082-Phospholipids,
pubmed-meshheading:2440082-Proteins,
pubmed-meshheading:2440082-Pulmonary Surfactants,
pubmed-meshheading:2440082-Rats,
pubmed-meshheading:2440082-Rats, Inbred F344
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pubmed:year |
1987
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pubmed:articleTitle |
Surfactant and physiologic alterations in an animal model of adult human lung disease. A preliminary report.
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pubmed:publicationType |
Journal Article
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