Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-5-26
pubmed:abstractText
In order to evaluate the preventive action of certain drugs in the formation of adhesions, three different types of trauma were induced in the uterine horns of 105 female Wistar rats. The animals were divided into six groups of 15 rats each and to each group was administered respectively: aprotinin i.p.; hydrocortisone i.p.; dextran 70 i.p.; colchicine i.p.; saline i.p.; colchicine i.m. One more group of 15 rats was left without treatment, as control. Four weeks later the adhesions were evaluated according to a qualitative/quantitative score and the results analysed using advanced statistical analysis. Aprotinin achieved the best results both in and around the trauma areas. Dextran produced an overall reduction of adhesions, but showed no specific effect on the trauma areas. The other substances failed to improve the adhesion situation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0587-2421
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-72
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Pharmacological prevention of postoperative adhesions experimentally induced in the rat.
pubmed:publicationType
Journal Article, Comparative Study