Linked Life Data

2430236

Source:http://linkedlifedata.com/resource/pubmed/id/2430236

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-12-17
pubmed:abstractText
Two distinct Ca currents may be recorded from guinea pig hippocampal CA1 neuronal somata: a non-inactivating (persistent) current and a rapidly inactivating (transient) current. Nimodipine, a 'calcium antagonist', reduced both Ca currents though the transient current was somewhat less sensitive than the persistent current. BAY K 8644, a 'calcium agonist' enhanced the persistent current and shifted the activation threshold for this current to more negative potentials. BAY K 8644 also enhanced the transient Ca current though the effect was very variable. The results demonstrate that Ca channels in hippocampal CA1 neurones possess a dihydropyridine receptor in common with Ca channels in other tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
110-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Interaction of 1,4-dihydropyridines with somatic Ca currents in hippocampal CA1 neurones of the guinea pig in vitro.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't