Linked Life Data

2427947

Source:http://linkedlifedata.com/resource/pubmed/id/2427947

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-10-23
pubmed:abstractText
Various strains, stocks, and clones of Trypanosoma cruzi were analyzed for neuraminidase (NA) activity using fetuin and human erythrocytes as substrate. In all cases the activity was found to be developmentally regulated. Zymodeme type I strains, which are histotropic for skeletal muscle, had greater NA activity than zymodeme type II strains which are histotropic for either macrophages or cardiac muscle cells. Heterogeneity of NA expression within strains is suggested by the finding that one Silvio X10 clone had greater NA activity than another clone of the same stock. The differences observed were more pronounced when human erythrocytes and not fetuin were used as substrate. Trypomastigotes of the high producing strains reared in bovine artery smooth muscle cells had enhanced expression compared to trypomastigotes reared in 3T3 or human fibroblast cells. The first harvest of trypomastigotes from cell cultures had greater NA activity than trypomastigotes harvested on subsequent days.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0166-6851
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Heterogeneous distribution of neuraminidase activity in strains and clones of Trypanosoma cruzi and its possible association with parasite myotropism.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't