Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-4-30
pubmed:abstractText
Cell pairs isolated from adult rat ventricles were used to characterize the electrical properties of the nexal membrane located between the cells. Each cell of a cell pair was connected to a suction pipette so as to enable whole-cell recordings. A double voltage-clamp method was employed which allowed the voltage gradient across the nexal membrane to be controlled. The current-voltage relationship of the nexal membrane was found to be linear over a broad range of transnexal voltages ( +/- 50 mV). The measurements revealed a mean value for the apparent nexal membrane resistance, rn(app), of 3.4 M omega. Taking into account the contribution of an uncompensated series resistance (access resistance), the effective nexal resistance, rn(eff), amounts to 1.7 M omega, approximately. The nexal membrane resistance was found to be insensitive to the sarcolemmal membrane potential, Vm (voltage range tested: -90 mV to +30 mV). The nexal membrane showed no rectifying property, i.e. it allows impulse transmission in both directions equally well. The connexons of the nexal membrane exhibited no time-dependent gating behaviour (time range investigated: 0.1-10 s).
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-1065540, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-1151835, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-1177142, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-13000763, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-13236475, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-13642302, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-14005158, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-14206423, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-14449163, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-19431545, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-201046, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-309942, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-366168, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-373599, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-373601, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4057088, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4303657, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4310255, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4319015, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4415790, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4578328, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4687914, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-4913702, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-5229812, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-5350329, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-5435783, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-5499801, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-5501485, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-624994, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6251204, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6259274, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6259275, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6270629, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6270711, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6296371, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6306241, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6308246, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6321740, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6323703, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6324658, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6607456, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6699787, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6750688, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6796679, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6875911, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-6887233, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-701371, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-7104446, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-7108778, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-7175743, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-7320902, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-864430, http://linkedlifedata.com/resource/pubmed/commentcorrection/2420974-963211
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
370
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-84
pubmed:dateRevised
2010-9-9
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Electrical properties of the nexal membrane studied in rat ventricular cell pairs.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't