| pubmed-article:2416849 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C0085732 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
| pubmed-article:2416849 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:2416849 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2416849 | pubmed:dateCreated | 1986-2-13 | lld:pubmed |
| pubmed-article:2416849 | pubmed:abstractText | This report describes an investigation of the abilities of different immunoassays to detect differences in affinities between related antigens for particular monoclonal antibodies. Nine different monoclonal antibodies were used and 6 strains of influenza virus represented closely related antigens. Parameters defining assay sensitivity were estimated experimentally for each antibody in 4 different immunoassays. Predicted failures of particular assays to detect differences in antigen affinities, based on these parameters, were demonstrated. One assay method failed to detect heteroclitic activity of 1 antibody which was clearly evident in the other 3 assays. As well as supporting theoretical models of assay sensitivity derived in the preceding paper the experiments demonstrated a significant effect of antibody subclass. | lld:pubmed |
| pubmed-article:2416849 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2416849 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2416849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416849 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2416849 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2416849 | pubmed:issn | 0022-1759 | lld:pubmed |
| pubmed-article:2416849 | pubmed:author | pubmed-author:UnderwoodP... | lld:pubmed |
| pubmed-article:2416849 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2416849 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:2416849 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:2416849 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2416849 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2416849 | pubmed:pagination | 309-23 | lld:pubmed |
| pubmed-article:2416849 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:meshHeading | pubmed-meshheading:2416849-... | lld:pubmed |
| pubmed-article:2416849 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:2416849 | pubmed:articleTitle | Practical considerations of the ability of monoclonal antibodies to detect antigenic differences between closely related variants. | lld:pubmed |
| pubmed-article:2416849 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2416849 | pubmed:publicationType | Comparative Study | lld:pubmed |
