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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1985-9-6
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pubmed:abstractText |
The concentration of latamoxef sodium (LMOX) in serum and prostatic tissue was evaluated. Thirty seven patients with benign prostatic hypertrophy were given 1 g LMOX intravenously prior to prostatectomy. Prostatic tissue and blood were sampled at 1, 2 or 3 hrs after administration of LMOX. The concentration of LMOX in prostatic tissue was 17.4 +/- 3.4 micrograms/g tissue, 11.1 +/- 1.3 microgram/g tissue and 8.9 +/- 1.3 microgram/g tissue 1, 2 and 3 hrs after injection, respectively (mean +/- S.E.). The penetration ratio of LMOX (concentration in tissue/in serum) to prostate was 30-45%. Therefore, the 80% MIC of LMOX is lower than 8 micrograms/ml for most gram negative bacteria, the results suggest that LMOX is very effective against prostatitis caused by these organisms.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0018-1994
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
539-43
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2411116-Aged,
pubmed-meshheading:2411116-Anti-Bacterial Agents,
pubmed-meshheading:2411116-Humans,
pubmed-meshheading:2411116-Injections, Intravenous,
pubmed-meshheading:2411116-Male,
pubmed-meshheading:2411116-Middle Aged,
pubmed-meshheading:2411116-Moxalactam,
pubmed-meshheading:2411116-Premedication,
pubmed-meshheading:2411116-Prostate,
pubmed-meshheading:2411116-Prostatectomy,
pubmed-meshheading:2411116-Prostatic Hyperplasia,
pubmed-meshheading:2411116-Prostatitis
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pubmed:year |
1985
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pubmed:articleTitle |
[Concentration level of latamoxef sodium (LMOX) in prostatic tissue].
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pubmed:publicationType |
Journal Article,
English Abstract
|