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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1976-4-15
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pubmed:abstractText |
Chronic graft-versus-host (GVH) disease was induced in NZB/NZW F1 (B/W) hybrid female mice by the weekly injection of parental NZB spleen cells. Control mice received injections of syngeneic spleen cells only. The mice were assayed for antibodies to [3H]DNA and [3H]polyadenylic-polyuridylic acid by a cellulose ester filter radioimmunoassay, and for antibody to thymocytes by a cytotoxicity method. GVH disease accelerated the development of all three antibodies in B/W mice. In addition, sucrose density gradient ultracentrifugation of pooled sera suggested that an accelerated switch from 19S to 7S anti-DNA production may be an early effect of GVH. The mechanism of acceleration is discussed in terms of immunological and viral factors generated by the GVH reaction.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-13730732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4105624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4109111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4115708,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4116319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4123818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4146378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4149592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4169964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4200650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4273650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4288700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4325310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4392713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4395204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4400648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4401006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4404278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4509164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4538858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4550607,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4611671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4757871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4877346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-4877426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5003632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5035244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5283928,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5304991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5495398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5523966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5828031,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2403-5918139
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-85
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2403-Animals,
pubmed-meshheading:2403-Autoantibodies,
pubmed-meshheading:2403-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:2403-DNA,
pubmed-meshheading:2403-Female,
pubmed-meshheading:2403-Graft vs Host Reaction,
pubmed-meshheading:2403-Mice,
pubmed-meshheading:2403-Mice, Inbred NZB,
pubmed-meshheading:2403-Poly A-U,
pubmed-meshheading:2403-RNA,
pubmed-meshheading:2403-T-Lymphocytes
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pubmed:year |
1975
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pubmed:articleTitle |
Acceleration of autoimmunity in NZB/NZW F1 mice by graft-versus-host disease.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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