Linked Life Data

2400332

Source:http://linkedlifedata.com/resource/pubmed/id/2400332

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-10-16
pubmed:abstractText
Localization of apoprotein E (apo E) has been studied in different human tissues. For this aim the immunoperoxidase method and peroxidase-antiperoxidase complex, polyclonal and monoclonal antibodies, to apo E have been used. In every human tissue analysed apo E-containing cells have been revealed. To the latter the following cell types belong: hepatocytes and hepatic sinusoidal cells, macrophages of the spleen, lymph nodes and pulmonary tissues, glial cells and cells in all layers of the adrenals, skin keratinocytes, cells of the glomerular capsule and convoluted tubules of the kidney, spermatocytes and smooth muscle cells of the testis. Besides, apo E is revealed in endothelium of some vessels. As demonstrate the results obtained, apo E is found practically in all human tissues. A suggestion is made that besides its participation in reverse cholesterol transport, this protein performs a number of additional functions, such as regulation of local hormonal homeostasis of an organ.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0004-1947
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Immunocytochemical analysis of apoprotein E distribution in human tissues].
pubmed:publicationType
Journal Article, English Abstract