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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1990-10-12
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pubmed:abstractText |
An 85-year-old male with cardiac failure secondary to anaemia had an apparent anti-Ge2 (Ge = Gerbich) in his serum which did not agglutinate his own red cells even though they were Ge-positive in tests with alloanti-Ge. The direct antiglobulin test was negative; however, an antibody with apparent anti-Ge2 specificity was eluted from his red cells. The patient's autoantibody was shown in immunoblotting experiments to react with an antigenic determinant on beta-sialoglycoprotein. This case illustrates that an autoanti-Ge can masquerade as an alloantibody, thereby complicating antibody identification, and implies that the immunochemical specificity of autoanti-Ge2 is different from that of alloanti-Ge2.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0042-9007
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
287-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2399694-Aged,
pubmed-meshheading:2399694-Aged, 80 and over,
pubmed-meshheading:2399694-Anemia,
pubmed-meshheading:2399694-Antibody Specificity,
pubmed-meshheading:2399694-Autoantibodies,
pubmed-meshheading:2399694-Blood Transfusion,
pubmed-meshheading:2399694-Cardiac Output, Low,
pubmed-meshheading:2399694-Humans,
pubmed-meshheading:2399694-Isoantibodies,
pubmed-meshheading:2399694-Male
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pubmed:year |
1990
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pubmed:articleTitle |
Serological and immunochemical specificity of a human autoanti-Gerbich-like antibody.
|
pubmed:affiliation |
Blood Group Reference Laboratory, Bristol, UK.
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pubmed:publicationType |
Journal Article,
Case Reports
|