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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-10-10
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pubmed:abstractText |
Clinical experience is recorded and summarized with the application of BCG vaccine for prophylaxis, treatment and immunochemotherapy of bladder tumors for the period June 1985-January 1988. Included in the study were 85 patients distributed in five groups: 23 patients treated for prevention of relapses; 26 treated for existing and residual surface tumors; 13 in whom BCG vaccine F-70 was applied for prophylaxis purpose; 17 with surface tumors treated only surgically--control group; 10 patients with advanced bladder tumor treated with immunochemotherapeutic agents. Once the results have been reported and discussed, the following inferences were made: 1. Intravesical BCG vaccine is a new effective and practicable method for prophylaxis and treatment of surface bladder tumors; 2. A 12-month course of treatment with the new Bulgarian Kalgevax showed high therapeutic activity; 3. Indications and possibilities for treatment of existing and residual surface tumors with intravesical BCG vaccine are given; complete effect of treatment was obtained in 21 patients (81 per cent); 4. The side reactions of the application of BCG vaccine and the possibilities for their reduction are presented; 5. The first results of application of immunotherapy in advanced bladder tumors are encouraging.
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pubmed:language |
bul
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0450-2167
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
48-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2395285-Administration, Intravesical,
pubmed-meshheading:2395285-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:2395285-BCG Vaccine,
pubmed-meshheading:2395285-Cisplatin,
pubmed-meshheading:2395285-Combined Modality Therapy,
pubmed-meshheading:2395285-Cyclophosphamide,
pubmed-meshheading:2395285-Drug Evaluation,
pubmed-meshheading:2395285-Epirubicin,
pubmed-meshheading:2395285-Humans,
pubmed-meshheading:2395285-Immunotherapy,
pubmed-meshheading:2395285-Injections, Intradermal,
pubmed-meshheading:2395285-Neoplasm Recurrence, Local,
pubmed-meshheading:2395285-Postoperative Care,
pubmed-meshheading:2395285-Urinary Bladder Neoplasms
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pubmed:year |
1990
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pubmed:articleTitle |
[Nonspecific immunotherapy with BCG vaccine in bladder tumors].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|