Linked Life Data

2392924

Source:http://linkedlifedata.com/resource/pubmed/id/2392924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-10-3
pubmed:abstractText
The purpose of the present work was to analyze the role of PgE2 and indomethacin in the regulation of immune response. 18 patients with laryngeal cancer were chosen for the study. Three cultures on peripheral venous blood were taken from each subject in order to evaluate the variation in the different lymphocyte groups after the addition of PgE2 and its inhibiting factor: indomethacin. In the cultures with PgE2, an increase in T suppressor lymphocytes was observed while the T helper group showed a significant reduction (cultures with indomethacin produced the opposite effect). This result bears witness to the inhibiting effect PgE2 has on the immune system in subjects with laryngeal cancer. On the basis of these results, while awaiting further data, it can be suggested that future therapy be based on the administration of indomethacin in patients suffering from this disease.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-100X
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-8
pubmed:dateRevised
2009-7-23
pubmed:meshHeading
pubmed:articleTitle
[Prostaglandins, suppressive action cells and carcinoma of the larynx: preliminary data].
pubmed:affiliation
I Clinica Otorinolaringoiatrica dell'Università di Torino.
pubmed:publicationType
Journal Article, In Vitro, English Abstract