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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-9-7
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pubmed:abstractText |
Osteoporosis and fractures are rare in acromegaly. An 84-year-old acromegalic woman sustained a fractured neck of femur in a fall. Histomorphometric analysis of an iliac crest biopsy showed marked osteoporosis and augmented resorption parameters. Cortical plates were very thin and bone volume was 8.5%; 12.5% is the reference value for women at this age. The total resorption surfaces were 23.7% compared with the reference value of 8%. We conjecture that postmenopausal and involutional osteoporosis were far advanced before the development of acromegaly, explaining the coexistence of the two conditions. Parathormone (65 pmol/l) and 24,25-dihydroxyvitamin D (1.34 ng/ml) levels were within normal limits, but those of 25-hydroxyvitamin D (5.6 ng/ml) and 1,25-dihydroxyvitamin D (15 pg/ml) were markedly decreased.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-2180
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
280-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2380027-Acromegaly,
pubmed-meshheading:2380027-Aged,
pubmed-meshheading:2380027-Aged, 80 and over,
pubmed-meshheading:2380027-Biopsy,
pubmed-meshheading:2380027-Bone Resorption,
pubmed-meshheading:2380027-Calcitriol,
pubmed-meshheading:2380027-Female,
pubmed-meshheading:2380027-Femoral Neck Fractures,
pubmed-meshheading:2380027-Humans,
pubmed-meshheading:2380027-Hydroxycholecalciferols,
pubmed-meshheading:2380027-Ilium,
pubmed-meshheading:2380027-Osteoporosis, Postmenopausal,
pubmed-meshheading:2380027-Parathyroid Hormone,
pubmed-meshheading:2380027-Vitamin D
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pubmed:year |
1990
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pubmed:articleTitle |
Acromegaly and proximal femoral fracture in an aged person: bone histomorphometry, vitamin D metabolites and parathormone.
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pubmed:affiliation |
Department of Geriatric Medicine, Soroka Medical Center, Beer Sheva, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports
|