Linked Life Data

2379135

Source:http://linkedlifedata.com/resource/pubmed/id/2379135

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-9-7
pubmed:abstractText
An in vitro-in vivo approach was used to examine the effect of selected cell proliferation on the progression to cancer. Liver cells isolated from rat donors with nodular livers were kept for 3 h in vitro, transferred to spleens and livers of syngeneic recipients and assessed at 4 and 10 months for evidence of cancer. Ten months after transfer of one million nodular liver cells (40% were GST-P + hepatocytes) to each of 50 recipients, 13 rats developed 21 hepatocellular cancers in their spleens (11 cancers) and livers. The latency to cancer was shortened by exposure to 2-acetylaminofluorene of the recipient rats at the time of hepatocyte transfer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Hepatocellular cancer development in spleen of syngenic rats after transfer of potential precursor hepatocytes.
pubmed:affiliation
Department of Pathology, University of Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't