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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-9-13
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pubmed:abstractText |
The method of fluorescence dequenching was used to study the interaction between influenza virus A/Krasnodar/101/59 and Namalwa and Raji lymphoblastoid cells. Experiments with endocytosis inhibitors and fluorescence quenchers have shown that at pH = 5.0 the virus lipid envelopes are fused with the plasma membranes of the cells, and at pH = 7.4 the virus lipid envelopes are fused with the internal, presumably endosomal, membranes of the cells. Remantadine at a concentration of 50-1000 micrograms/ml did not influence the fusion of virus lipid envelopes with intracellular membranes at pH = 7.4 whereas at pH = 5.0 it inhibited, beginning from 25 micrograms/ml concentration, the fusion of virus lipid envelopes with the plasma membranes of cells.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0365-9615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
483-5
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:2378964-Adamantane,
pubmed-meshheading:2378964-Animals,
pubmed-meshheading:2378964-Cell Line,
pubmed-meshheading:2378964-Cell Membrane,
pubmed-meshheading:2378964-Chick Embryo,
pubmed-meshheading:2378964-Endocytosis,
pubmed-meshheading:2378964-Fluorescent Dyes,
pubmed-meshheading:2378964-Hydrogen-Ion Concentration,
pubmed-meshheading:2378964-Influenza A virus,
pubmed-meshheading:2378964-Membrane Lipids,
pubmed-meshheading:2378964-Rimantadine
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pubmed:year |
1990
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pubmed:articleTitle |
[Effects of remantadine on fusion of lipid membranes of influenza A virus with plasma and internal membranes of lymphoblastic cells].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|