|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0008630,
umls-concept:C0015576,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0043381,
umls-concept:C0079429,
umls-concept:C0205147,
umls-concept:C0205314,
umls-concept:C0679622,
umls-concept:C0680022,
umls-concept:C1171362,
umls-concept:C1515670
|
|
pubmed:issue |
6281
|
|
pubmed:dateCreated |
1990-8-30
|
|
pubmed:abstractText |
A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0028-0836
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
19
|
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pubmed:volume |
346
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
245-50
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2374589-Amino Acid Sequence,
pubmed-meshheading:2374589-Animals,
pubmed-meshheading:2374589-Base Sequence,
pubmed-meshheading:2374589-Chromosome Deletion,
pubmed-meshheading:2374589-Chromosome Mapping,
pubmed-meshheading:2374589-Cloning, Molecular,
pubmed-meshheading:2374589-DNA-Binding Proteins,
pubmed-meshheading:2374589-Female,
pubmed-meshheading:2374589-Male,
pubmed-meshheading:2374589-Mice,
pubmed-meshheading:2374589-Molecular Sequence Data,
pubmed-meshheading:2374589-Mutation,
pubmed-meshheading:2374589-Nucleic Acid Hybridization,
pubmed-meshheading:2374589-Restriction Mapping,
pubmed-meshheading:2374589-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2374589-Sex Determination Analysis,
pubmed-meshheading:2374589-Testis,
pubmed-meshheading:2374589-Y Chromosome
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.
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|
pubmed:affiliation |
Laboratory of Eukaryotic Molecular Genetics, MRC National Institute for Medical Research, Mill Hill, London, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
