Linked Life Data

2364285

Source:http://linkedlifedata.com/resource/pubmed/id/2364285

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-8-13
pubmed:abstractText
We studied whether plasticity-induced callosal transfer exists after the critical period for sensitivity of visual cortex cells in kittens postnatally monocularly deprived and in which interocular competition was cancelled by chiasm transection during adulthood. Callosal transfer was studied acutely (n = 3 cats) and chronically (n = 7) following the chiasm transection (OCAMD). For comparison, adult cats in which chiasm transection only was performed (OCA) were also studied acutely (n = 3) and chronically (n = 9). The results were also compared to cats in which monocular deprivation and chiasm transection were simultaneously performed (OCKMD) during development (n = 6) and to normal control cats (n = 18). Unit recording was extracellularly carried out in visual cortex areas 17 and 18 and their boundary region, where the corpus callosum is represented. When no interocular competition was allowed between the non-deprived and the deprived eye via the thalamocortical direct visual pathways on cortical cells, such as in the OCKMD cats, the absolute majority of the cells were ipsilaterally driven, regardless of which hemisphere was studied. Only a minor proportion (4.1%) of the cells had some contralateral input from the non-deprived eye in the hemisphere ipsilateral to the deprived eye, indicating almost no interhemispheric callosal transfer. A slight increase in the proportion of cells callosally driven from the non-deprived eye (9.8%), was found in this hemisphere in cats in which interocular competition was allowed via the direct visual pathways prior to its cancellation by chiasm transection (OCAMD), if studied acutely after the chiasm transection. A remarkable increase in callosal transfer was found in this hemisphere under chronic conditions.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
516
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
84-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Post-critical period plasticity of callosal transfer to visual cortex cells of cats following early conditioning of monocular deprivation and late optic chiasm transection.
pubmed:affiliation
Physiological Laboratory, Maurice and Gabriela Goldschleger Eye Research Institute, Tel-Aviv University Faculty of Medicine, Chaim Sheba, Medical Center, Tel-Hashomer, Israel.
pubmed:publicationType
Journal Article