rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1990-7-20
|
pubmed:abstractText |
Immunoreactivity to epidermal growth factor receptor (EGFR) was present in the brain vasculature of 13/13 demented elderly patients, but absent in 9/11 non-demented elderly patients. Of the two positive non-demented patients, one had significant Alzheimer's pathology and the other spinal carcinoma. Ultrastructurally, EGFR is localized to the lumenal surface of endothelial cells.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0006-8993
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
2
|
pubmed:volume |
512
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
347-52
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:2354367-Aged,
pubmed-meshheading:2354367-Aged, 80 and over,
pubmed-meshheading:2354367-Aging,
pubmed-meshheading:2354367-Brain,
pubmed-meshheading:2354367-Dementia,
pubmed-meshheading:2354367-Endothelium, Vascular,
pubmed-meshheading:2354367-Female,
pubmed-meshheading:2354367-Humans,
pubmed-meshheading:2354367-Immunohistochemistry,
pubmed-meshheading:2354367-Male,
pubmed-meshheading:2354367-Middle Aged,
pubmed-meshheading:2354367-Receptor, Epidermal Growth Factor
|
pubmed:year |
1990
|
pubmed:articleTitle |
Epidermal growth factor receptor expression in demented and aged human brain.
|
pubmed:affiliation |
Department of Zoology, Arizona State University, Tempe 85287.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|