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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1990-7-17
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pubmed:abstractText |
Wet mass, resting membrane potential, frequency of miniature end-plate potentials and the concentration of [3H]ouabain-binding sites were studied after 7 days' immobilization of the rat soleus and extensor digitorum longus (EDL) muscles in the shortened or stretched position and after 3 and 7 days of remobilization. We observed that the loss of muscle mass by 37% in the rat soleus immobilized for 7 days in the shortened position is accompanied by a membrane depolarization of about 5 mV, a decrease in frequency of miniature end-plate potentials by 60% and a decrease of [3H]ouabain binding by 25%. Only minor changes were found in stretched soleus and in shortened and stretched EDL. After 3 days of remobilization of stretched soleus the muscle mass, [3H]ouabain binding and miniature end-plate potential frequency recovered to control values but the resting membrane potential continued to decrease. All changes induced by immobilization disappeared on day 7 of remobilization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0031-6768
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
416
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
126-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2352829-Animals,
pubmed-meshheading:2352829-Atrophy,
pubmed-meshheading:2352829-Binding Sites,
pubmed-meshheading:2352829-Immobilization,
pubmed-meshheading:2352829-Male,
pubmed-meshheading:2352829-Membrane Potentials,
pubmed-meshheading:2352829-Motor Endplate,
pubmed-meshheading:2352829-Muscle Contraction,
pubmed-meshheading:2352829-Muscles,
pubmed-meshheading:2352829-Ouabain,
pubmed-meshheading:2352829-Rats,
pubmed-meshheading:2352829-Rats, Inbred Strains,
pubmed-meshheading:2352829-Time Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Immobilization atrophy and membrane properties in rat skeletal muscle fibres.
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pubmed:affiliation |
Institute of Physiology, Czechoslovak Academy of Sciences, Prague.
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pubmed:publicationType |
Journal Article
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