Linked Life Data

2352163

Source:http://linkedlifedata.com/resource/pubmed/id/2352163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-7-16
pubmed:abstractText
New indirect spectrophotometric methods of analysis of tobramycin using the derivatizing agents o-phthaldialdehyde, fluorescamine, and dansyl chloride were developed and compared with existing methods. Optimum reaction conditions were established for the complex formation between tobramycin and each reagent. The sensitivity and reproducibility of these new procedures were compared with results obtained using published methods. Of the new methods, the o-phthaldialdehyde and fluorescamine procedures were more sensitive and reproducible than the dansyl chloride procedure. Further, these procedures were subsequently applied to the analysis of aqueous solutions of other aminoglycosides including amikacin, neomycin, gentamicin, and kanamycin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-3549
pubmed:author
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
428-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Comparison of new and existing spectrophotometric methods for the analysis of tobramycin and other aminoglycosides.
pubmed:affiliation
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha 68105.
pubmed:publicationType
Journal Article, Comparative Study