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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1990-7-13
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pubmed:abstractText |
From 1 September 1981 to 1 January 1987, 118 patients with FIGO Stage IB, IC, IIA, IIB, and IIC epithelial ovarian cancer were randomized to abdominal irradiation or pelvic irradiation + cyclophosphamide. There was no difference between the regimens with respect to recurrence-free survival (55%) and 4-year overall survival (63%). At routine second-look laparotomy, 16% of patients without clinical detectable tumor showed recurrence. Twenty-five percent of the patients treated with pelvic irradiation + cyclophosphamide had hemorrhagic cystitis, probably caused by radiation damage and cyclophosphamide cystitis. Eight percent had late gastrointestinal symptoms requiring surgery.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0090-8258
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
367-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2351321-Abdomen,
pubmed-meshheading:2351321-Aged,
pubmed-meshheading:2351321-Cyclophosphamide,
pubmed-meshheading:2351321-Female,
pubmed-meshheading:2351321-Humans,
pubmed-meshheading:2351321-Intestines,
pubmed-meshheading:2351321-Laparotomy,
pubmed-meshheading:2351321-Neoplasm Recurrence, Local,
pubmed-meshheading:2351321-Ovarian Neoplasms,
pubmed-meshheading:2351321-Patient Compliance,
pubmed-meshheading:2351321-Pelvis,
pubmed-meshheading:2351321-Radiation Injuries,
pubmed-meshheading:2351321-Random Allocation,
pubmed-meshheading:2351321-Reoperation,
pubmed-meshheading:2351321-Survival Analysis
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pubmed:year |
1990
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pubmed:articleTitle |
Randomized study of whole-abdomen irradiation versus pelvic irradiation plus cyclophosphamide in treatment of early ovarian cancer.
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pubmed:affiliation |
Department of Oncology, Arhus University Hospital, Denmark.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|