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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1975-4-11
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pubmed:abstractText |
To determine whether in the management of pulmonary failure, the maximum compliance produced by positive end-expiratory pressure coincides with optimum lung function, 15 normovolemic patients requiring mechanical ventilation for acute pulmonary failure were studied. The end-expiratory pressure resulting in maximum oxygen transport (cardiac output times arterial oxygen content) and the lowest dead-space fraction both resulted in the greatest total static compliance. This end-expiratory pressure varied between 0 and 15 cm of water and correlated inversely with functional residual capacity at zero end-expiratory pressure (r equal -0.72, p less than or equal to 0.005). Mixed venous oxygen tension increased between zero end-expiratory pressure and the end-expiratory pressure resulting in maximum oxygen transport, but then decreased at higher end-expiratory pressures. When measurements of cardiac output or of true mixed venous blood are not available, compliance may be used to indicate the end-expiratory pressure likely to result in optimum cardiopulmonary function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0028-4793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
292
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
284-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:234174-Adult,
pubmed-meshheading:234174-Aged,
pubmed-meshheading:234174-Airway Resistance,
pubmed-meshheading:234174-Carbon Dioxide,
pubmed-meshheading:234174-Cardiac Output,
pubmed-meshheading:234174-Female,
pubmed-meshheading:234174-Helium,
pubmed-meshheading:234174-Humans,
pubmed-meshheading:234174-Hydrogen-Ion Concentration,
pubmed-meshheading:234174-Lung,
pubmed-meshheading:234174-Lung Compliance,
pubmed-meshheading:234174-Male,
pubmed-meshheading:234174-Middle Aged,
pubmed-meshheading:234174-Oxygen,
pubmed-meshheading:234174-Positive-Pressure Respiration,
pubmed-meshheading:234174-Pressure,
pubmed-meshheading:234174-Pulmonary Emphysema,
pubmed-meshheading:234174-Respiration,
pubmed-meshheading:234174-Respiratory Insufficiency,
pubmed-meshheading:234174-Spirometry
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pubmed:year |
1975
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pubmed:articleTitle |
Optimum end-expiratory airway pressure in patients with acute pulmonary failure.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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