rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1990-6-27
|
pubmed:abstractText |
1. We have tested the effect of taurine on nociceptive stimulation provoked by chemical agent (acetic acid) and by the hot-plate test. 2. In the acetic acid test, taurine exerts an antinociceptive effect at every dose and time assayed. The observed effect was dose-related. 3. Naxolone pretreatment antagonizes the antinociceptive effect of taurine in the acetic acid test. 4. The results obtained in hot-plate test show that taurine did not significantly affect latency time for paw licking.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0306-3623
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
333-6
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2341021-Acetic Acid,
pubmed-meshheading:2341021-Acetic Acids,
pubmed-meshheading:2341021-Analgesics,
pubmed-meshheading:2341021-Animals,
pubmed-meshheading:2341021-Dose-Response Relationship, Drug,
pubmed-meshheading:2341021-Mice,
pubmed-meshheading:2341021-Naloxone,
pubmed-meshheading:2341021-Pain,
pubmed-meshheading:2341021-Reaction Time,
pubmed-meshheading:2341021-Taurine
|
pubmed:year |
1990
|
pubmed:articleTitle |
Antinociceptive effect of taurine and its inhibition by naxolone.
|
pubmed:affiliation |
Department of Pharmacology, Seville University Medical School, Spain.
|
pubmed:publicationType |
Journal Article
|