Linked Life Data

2340316

Source:http://linkedlifedata.com/resource/pubmed/id/2340316

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-6-28
pubmed:abstractText
The synthesis of androstenedione (AD) metabolites in liver microsomes of control and phenobarbital (PB)-induced male and female Wistar rats was studied. In liver microsomes of non-induced male rats the predominant formation of 16 alpha-hydroxyandrostenedione was observed, whereas in females the predominant form was the 7 alpha-metabolite. Induction of animals of both sexes with PB was accompanied by an increase in the 16 beta-hydroxylase activity. The dynamics of synthesis of other AD metabolites specifically produced by such cytochrome P-450 forms as P-450a, P-450h and P-450p was investigated. The specificity of metabolism of androstenedione by multiple forms of cytochrome P-450 is postulated.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0320-9725
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
308-14
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Evaluation of catalytic activity of multiple forms of cytochrome P-450 in liver microsomes of Wistar rats by androstenedione metabolism].
pubmed:publicationType
Journal Article, English Abstract